MITOCHONDRIAL DYSFUNCTION INDUCES RNA INTERFERENCE IN C. ELEGANS THROUGH A PATHWAY HOMOLOGOUS TO THE MAMMALIAN RIG-I ANTIVIRAL RESPONSE.

Mitochondrial dysfunction induces RNA interference in C. elegans through a pathway homologous to the mammalian RIG-I antiviral response.

RNA click here interference (RNAi) is an antiviral pathway common to many eukaryotes that detects and cleaves foreign nucleic acids.In mammals, mitochondrially localized proteins such as mitochondrial antiviral signaling (MAVS), retinoic acid-inducible gene I (RIG-I), and melanoma differentiation-associated protein 5 (MDA5) mediate antiviral respon

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Influenza Antigens NP and M2 Confer Cross Protection to BALB/c Mice against Lethal Challenge with H1N1, Pandemic H1N1 or H5N1 Influenza A Viruses

Influenza hemagglutinin (HA) is considered a major protective antigen of seasonal click here influenza vaccine but antigenic drift of HA necessitates annual immunizations using new circulating HA versions.Low variation found within conserved non-HA influenza virus (INFV) antigens may maintain protection with less frequent immunizations.Conserved an

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Analysis of polymorphisms, promoter methylation, and mRNA expression profile of maternal and placental P53 and P21 genes in preeclamptic and normotensive pregnant women

Abstract Background Preeclampsia (PE), as a multisystem disorder, is associated with maternal hypertension and proteinuria.Apoptosis seems to be involved in the pathophysiology of PE, although its precise pathogenic mechanisms are not well established.In this study, we aimed to identify the association between maternal TP53-rs1042522, P21-rs1801270

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Anamorphic and Local Characterization of a Holographic Data Storage System with a Liquid-Crystal on Silicon Microdisplay as Data Pager

In this paper, we present a method to characterize a complete optical Holographic Data Storage System (HDSS), where we identify the elements that limit the capacity to register and restore the information introduced by means of a Liquid Cristal on Silicon (LCoS) microdisplay click here as the data pager.In the literature, it has been shown that LCo

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